Peer-reviewed veterinary case report
Hematuria and weight loss in a mare with pancreatic adenocarcinoma.
- Journal:
- The Cornell veterinarian
- Year:
- 1992
- Authors:
- Carrick, J B et al.
- Affiliation:
- Department of Large Animal Medicine · United States
- Species:
- horse
Plain-English summary
A clinical report described an 11-year-old Thoroughbred mare who was losing weight and had blood in her urine. The veterinarian suspected she had a tumor affecting her urinary system. Although a biopsy of a mass near her kidneys didn't show any abnormal cells, they found large irregular cells in the fluid around her lungs and abdomen. When the mare was examined after she passed away, they discovered multiple firm lumps throughout her abdomen, which were identified as pancreatic adenocarcinoma (a type of cancer that affects the pancreas). This case is notable because it is the first time pancreatic cancer has been linked to problems in the urinary system.
Abstract
This clinical report describes an 11-yr-old Thoroughbred mare that presented with clinical signs of weight loss and hematuria. History and clinical findings suggested the mare had neoplasia of the urogenital system. Although ultrasound-guided biopsy of the perirenal mass did not yield abnormal cells, large irregular cells were isolated from the thoracic and peritoneal fluid. At necropsy, multiple firm nodules were disseminated throughout the peritoneal cavity. Histological examination of the nodules revealed cells that were consistent with a pancreatic exocrine adenocarcinoma. This is the first report of pancreatic adenocarcinoma causing dysfunction of the urogenital system.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/1740064/