Peer-reviewed veterinary case report
Hemodialysis for treatment of oxytetracycline-induced acute renal failure in a neonatal foal.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1993
- Authors:
- Vivrette, S et al.
- Affiliation:
- Veterinary Medical Teaching Hospital · United States
- Species:
- horse
Plain-English summary
A 4-day-old foal developed acute kidney failure after receiving oxytetracycline, a medication given to treat a tendon issue. Initial treatment with fluids and other medications helped a little but didn't fix the kidney problem. The foal underwent three sessions of hemodialysis over four days, which led to noticeable improvement in its condition and brought its blood values back to normal. This case suggests that hemodialysis can be a helpful option for treating kidney failure in foals when other treatments don't work.
Abstract
Acute renal failure in a 4-day-old foal secondary to oxytetracycline toxicosis was treated by hemodialysis. Oxytetracycline had been administrered as treatment for forelimb flexor tendon contracture. Conservtive treatment with fluids, furosemide, and dopamine partially alleviated serum electrolyte concentration imbalances, but was ineffective in promoting diuresis or decreasing azotemia. Three hemodialysis treatments over 4 days were administered, after which the clinical appearance of the foal improved, and biochemical and electrolyte values returned to within reference ranges. The nephrotoxic potential of oxytetracycline should be considered prior to its administration. Hemodialysis may be a treatment option in management of acute renal failure in foals that are nonresponsive to conservative medical treatment.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/8407440/