Peer-reviewed veterinary case report
Horses with severe kidney issues and swelling - what to know
By Morris, C F et al.·Published in Journal of the American Veterinary Medical Association·1987·School of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Hemolytic uremic-like syndrome in two horses.
- Species:
- horse
Plain-English summary
Two horses were diagnosed with a serious condition that caused them to produce very little urine, have high levels of waste products in their blood, and develop swelling in their abdomen and groin. Despite receiving treatment with fluids, medications to help them urinate, and steroids given through an IV, their condition did not improve, and they were put to sleep to prevent further suffering. A closer examination of their tissues showed severe damage to their blood vessels and a lot of clotting material in their kidneys and lymph nodes. The symptoms these horses experienced were similar to a condition known as hemolytic-uremic syndrome, which affects humans. Unfortunately, the treatment did not work.
Abstract
A syndrome characterized clinically by oliguria, progressive severe azotemia, and edema of the abdomen and groin was seen in 2 horses. Treatment with fluids, diuretics, and corticosteroids administered intravenously was ineffective, and the horses were euthanatized. Microscopically, there was severe necrotizing angiopathy with profuse fibrin deposition in renal glomeruli and sinusoids of peripheral lymph nodes. The signs observed in the horses resembled hemolytic-uremic syndrome in human beings.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/3692994/