Peer-reviewed veterinary case report
Colts with hemophilia A - signs and outcomes
By Henninger, R W·Published in Journal of the American Veterinary Medical Association·1988·South Plains Veterinary Clinic·View original on PubMed →
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Original publication title: Hemophilia A in two related quarter horse colts.
- Species:
- horse
Plain-English summary
Two related Quarter Horse colts were diagnosed with hemophilia A, a bleeding disorder that caused severe bleeding issues. One colt showed signs of difficulty breathing and swallowing due to a hematoma (a collection of blood) in the neck, while the other colt tragically died from internal bleeding. Blood tests confirmed the diagnosis by showing a deficiency in a specific clotting factor. Unfortunately, hemophilia A is a genetic condition that can be passed down, and in this case, it led to serious health complications for both colts.
People also search for: Quarter Horse colts bleeding disorder · hemophilia A symptoms in horses · horse difficulty breathing and swallowing
Abstract
Severe hemorrhagic diathesis caused by hemophilia A (factor VIII:C deficiency) was diagnosed in 2 related Quarter Horse colts. Clinical signs consisted of dyspnea and dysphagia attributable to cranial cervical hematoma in one colt and to intra-abdominal hemorrhage resulting in death of the second colt. Factor VIII:C deficiency, a defect of the intrinsic coagulation pathway, is suggested by results of coagulation studies--prolonged activated partial thromboplastin time, normal prothrombin time, and normal primary bleeding time. The diagnosis was confirmed by results of factor VIII:C assays. Hemophilia A is inherited as an X chromosome-linked trait.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/3138224/