Peer-reviewed veterinary case report
Heparin binding haemagglutin as potential diagnostic marker of Mycobacterium bovis.
- Journal:
- The new microbiologica
- Year:
- 2008
- Authors:
- Molicotti, Paola et al.
- Affiliation:
- Department of Biomedical Sciences · Italy
Abstract
In this study, we characterized the humoral responses in cattle of Sardinia. The animals were divided into three groups: 1) 28 cattle infected with Mycobacterium bovis; 2) 48 cattle from herds in which foci of infection was notified; 3) 50 cattle from herds that were TB-free. Levels of IgG antibody were measured against the following antigens of M. tuberculosis: Heparin-Binding-Haemagglutin (HBHA), Ag85B, PPE44, and PE_PGRS33 to investigate their potential to diagnose TB in animals. Our results indicated that HBHA is a potential candidate for the development of a serological assay for rapid diagnosis of cattle infected with M. bovis.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18843899/