Peer-reviewed veterinary case report
High chloride diet lowered seizure medicine in epileptic dog
By Shaw, N et al.·Published in Journal of the American Veterinary Medical Association·1996·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: High dietary chloride content associated with loss of therapeutic serum bromide concentrations in an epileptic dog.
- Species:
- dog
Plain-English summary
An 11-year-old Dachshund with epilepsy was successfully treated with bromide to control his seizures. However, after starting a special diet high in chloride, his bromide levels dropped, leading to a return of seizures. The high chloride content in the diet increased the elimination of bromide from his system, meaning he needed a higher dose to maintain seizure control. Adjusting his bromide dosage helped manage his seizures again, showing the importance of diet in treatment for dogs with epilepsy.
People also search for: dog seizures treatment · Dachshund epilepsy diet · bromide dosage for dogs
Abstract
Bromide treatment was successful in controlling seizures in an 11-year-old Dachshund with epilepsy and presumptive phenobarbital-associated hepatopathy. Because bromide does not induce liver enzyme activity and does not seem to be hepatotoxic, it can be used to control seizures in dogs with concurrent epilepsy and hepatic disease. In this dog, institution of a special calculolytic diet with high chloride content was associated with a decrease in serum bromide concentrations and the recurrence of seizures. High chloride intake increases the elimination of bromide in dogs, leading to higher dosage requirements for bromide in dogs fed high-chloride diets.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8567379/