Peer-reviewed veterinary case report
High-grade muscle tumor in a dog's groin area
By Hojo, Yuri et al.·Published in The Journal of veterinary medical science·2012·Tokyo University of Agriculture and Technology, Japan·View original on PubMed →
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Original publication title: High-grade myofibroblastic sarcoma of inguinal region in a dog.
- Species:
- dog
Plain-English summary
An 11-year-old female bloodhound was found to have a tumor in her left groin area. The tumor was aggressive and showed signs of extensive tissue damage. After examining the tumor cells, the veterinarian diagnosed it as a high-grade myofibroblastic sarcoma, which is a type of cancer. Treatment options would typically include surgery to remove the tumor, but the specifics of the treatment and outcome were not detailed.
People also search for: dog groin tumor · bloodhound cancer treatment · high-grade sarcoma in dogs
Abstract
A subcutaneous tumor in the left inguinal region was present in an 11-year-old female bloodhound. Histopathologically, the tumor showed invasive growth and extensive necroses, and it was composed of spindle-shaped, elongated, and stellate neoplastic cells accompanied by occasional giant cells arranged in fascicular, herringbone, or irregular storiform patterns with abundant production of collagen fibers. The cytoplasm of most tumor cells was positive for vimentin, alpha-smooth muscle actin, and calponin, but was negative for desmin, smoothelin, and S-100. Furthermore, most of the tumor cells were negative for Iba1 while some tumor cells were weakly positive. Thus, this tumor was diagnosed as a high-grade myofibroblastic sarcoma according to the diagnostic criteria for human myofibroblastic sarcomas.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22156390/