Peer-reviewed veterinary case report
Cat with cancerous tumor in ankle area and lymph node swelling
By Pinard, J et al.·Published in Veterinary pathology·2006·View original on PubMed →
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Original publication title: Histiocytic sarcoma in the tarsus of a cat.
- Species:
- cat
Plain-English summary
A 12-year-old Persian cat was brought to the vet because of a firm swelling on its right ankle and an enlarged lymph node behind the knee. Tests showed that the swelling was caused by cancer, specifically a type called histiocytic sarcoma, which is a rare tumor that can affect joints. Unfortunately, the cancer had spread into nearby tissues. This case is significant because it's the first time a histiocytic sarcoma has been reported in a cat's joint. Treatment options would typically depend on the extent of the disease and could include surgery or chemotherapy, but the outcome in this case was not detailed.
People also search for: cat ankle swelling · cat lymph node enlargement · histiocytic sarcoma in cats · cat joint cancer treatment
Abstract
A 12-year-old Persian cat was examined for a firm swelling of the right tarsal region and enlargement of the corresponding right popliteal lymph node. Cytologic evaluation demonstrated a population of malignant cells consistent with large cell lymphoma. Necropsy revealed a multi-lobulated subcutaneous mass involving the tarsus with some extension into adjacent deep muscular tissue. Histologically, the mass was composed of round cells with eosinophilic cytoplasm and pleomorphic anisokaryotic nuclei. Evidence of articular and nodal infiltration by these cells was observed. Differential diagnoses included synovial sarcoma and histiocytic sarcoma. Neoplastic cells were negative for cytokeratin, CD79a, and CD3 and positive for CD18, vimentin, lysozyme, and alpha-1-antitrypsin, most consistent with a diagnosis of histiocytic sarcoma. This is the first report of a histiocytic sarcoma involving a joint of a cat. The final diagnosis was based on the light microscopic appearance in combination with the immunohistochemical stains.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17099163/