Peer-reviewed veterinary case report
Dog melanomas on lip, skin, and nail bed outcomes and features
By Schultheiss, Patricia C·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2006·Department of Microbiology, United States·View original on PubMed →
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Original publication title: Histologic features and clinical outcomes of melanomas of lip, haired skin, and nail bed locations of dogs.
- Species:
- dog
Plain-English summary
A group of dogs with melanomas (a type of skin cancer) in their lips, nail beds, and other areas had their outcomes reviewed. For example, 32 dogs with malignant lip tumors faced a high risk, with 22 dying within a year, while 10 remained tumor-free after surgery. In contrast, most dogs with benign tumors in the lip or skin were tumor-free after a year. All nail bed tumors were malignant, but after digit amputation, 6 out of 14 dogs were tumor-free for at least a year. Unfortunately, the specific features of the tumors did not reliably predict how well a dog would do after treatment.
People also search for: dog lip melanoma treatment · dog nail bed tumor prognosis · skin cancer in dogs survival rate
Abstract
Outcomes, signalments, and the relationship of histologic features with the outcome of melanomas located in lip, nail bed, and haired skin of dogs were reviewed. These melanomas were diagnosed as benign or malignant based on histologic features. Melanomas of the lip arose from mucous membrane in most cases. 32 dogs with lip melanomas that had histologic features of malignancy, 22 died because of the tumor within 1 year and 10 were tumor free for at least 1 year following removal. Of 10 dogs with melanomas with benign histologic features on the mucous membrane of the lip, 9 were tumor free for at least 1 year. Of 4 dogs with benign appearing tumors of the haired skin of the lip, 3 were tumor free for at least 1 year. Melanomas with histologic features of malignancy occurred in many locations of haired skin, and 11 of 24 dogs were tumor free for at least 1 year. All nail bed melanomas had histologic features of malignancy and all invaded the third phalanx, but 6 of 14 dogs were tumor free for at least 1 year after amputation of the digit. Among these dogs, the 1-year survival rates for tumors classified as malignant by histologic features were 31% [corrected] for lip, 46% for haired skin, and 43% for nail bed. However, the clinical outcome of an individual malignant tumor could not be predicted accurately by any specific histologic features.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16921890/