Peer-reviewed veterinary case report
Feline bladder cancer cell types and tissue changes explained
By van der Weyden, Louise et al.·Published in Journal of comparative pathology·2021·Wellcome Sanger Institute, United Kingdom·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Histological Characterization of Feline Bladder Urothelial Carcinoma.
- Species:
- cat
Plain-English summary
A study looked at bladder cancer in cats, specifically a type called urothelial carcinoma, which is the most common bladder cancer in pets and people. Researchers examined tissue samples from 35 cats and found that the cancer could appear in different forms, with some tumors growing in a papillary shape and others forming tubular structures. The cancer's invasion into the bladder wall varied, and the appearance of the surrounding tissue also differed among cases. This research helps confirm that bladder cancer in cats shares many characteristics with similar tumors in dogs and humans.
People also search for: cat bladder cancer symptoms · feline urothelial carcinoma treatment · signs of cancer in cats
Abstract
Urothelial (transitional cell) carcinoma (UC) is the most common type of bladder cancer in humans, dogs and cats, although the incidence in cats is comparatively low. This retrospective study details the histopathological features of UC of the urinary bladder in 38 samples from 35 cats. Of the 38 samples, eight had a papillary architecture and in nine the tumour cells formed tubular or acinar structures. Tumour cell invasion of the bladder wall varied from confinement within the lamina propria or submucosa to transmural or extending to the serosa. The tumour stroma varied from sparse to abundant, with a scirrhous, myxomatous or mucinous appearance in eleven cases, three cases and one case, respectively. The degrees of tumour cell necrosis and inflammation were highly variable. We confirm that the histopathological features of bladder UC in cats have many similarities to the corresponding tumours in dogs and humans.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33494910/