Peer-reviewed veterinary case report
Eye inflammation and leishmaniosis in dogs explained
By Peña, M T et al.·Published in Journal of comparative pathology·2008·Departament de Medicina i Cirurgia Animals, Spain·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Histopathological features of ocular leishmaniosis in the dog.
- Species:
- dog
Plain-English summary
A study found that about 25% of dogs with leishmaniosis (a disease caused by parasites) can have eye problems. In this case, 60 dogs with confirmed leishmaniosis were examined after they died or were euthanized, and 15 of them showed visible eye issues. The researchers discovered inflammation and the presence of the parasite in various parts of the eye, including the conjunctiva and cornea. Some dogs received anti-protozoal treatment, but the study mainly focused on understanding the eye conditions related to leishmaniosis. This information can help veterinarians better diagnose and treat eye problems in dogs with this disease.
People also search for: dog leishmaniosis symptoms · dog eye problems treatment · why is my dog’s eye swollen · leishmaniosis in dogs · dog eye infection causes
Abstract
Canine leishmaniosis (CL) can present with multiple clinical signs and ocular disease is reported to occur in almost 25% of affected dogs. The purpose of the present study was to characterize the nature of inflammation within the eyes of dogs with leishmaniosis and to determine whether parasites were present in these lesions. Eyes from 60 dogs with confirmed leishmaniosis that died or were humanely destroyed over a 4 year period were included in the study. Sections of formalin-fixed globes were stained with haematoxylin and eosin (HE) and subjected to immunohistochemistry using a Leishmania-specific antibody. Clinically evident ocular signs were present in 15 of 60 dogs (13 bilaterally and 2 unilaterally). Thirty-five of 60 dogs received some form of anti-protozoal treatment. In 36 of 120 eyes (30%) a granulomatous inflammatory infiltrate was found and in 32 of 120 eyes (26.6%) the parasite was identified immunohistochemically within the globe. Ocular tissues affected, in order of frequency, were conjunctiva and limbus, ciliary body, iris, cornea, sclera and iridocorneal angle, choroid and the optic nerve sheath. Different microscopical patterns were defined in each of these structures. Leishmania organisms and associated inflammation can be found in different ocular tissues, accounting for some of the ocular clinical signs described for this disease.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18048051/