Peer-reviewed veterinary case report
Dog with skin and gum histoplasmosis causing granulomas
By Kagawa, Y et al.·Published in The Journal of veterinary medical science·1998·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Histoplasmosis in the skin and gingiva in a dog.
- Species:
- dog
Plain-English summary
An 8-year-old female mongrel dog had unusual grayish-white lumps on her skull and gums. These lumps were caused by a fungal infection called histoplasmosis, which was confirmed through special tests that identified yeast-like cells in the affected areas. The dog was diagnosed with this rare condition, marking the first reported case of canine histoplasmosis in Japan. Treatment details weren't provided, but early diagnosis and appropriate antifungal therapy are typically crucial for recovery in such cases.
People also search for: dog skin lumps treatment · histoplasmosis in dogs · dog gingivitis symptoms · fungal infection in dogs
Abstract
An 8-year-old, female mongrel dog had granulomatous lesions in the skull skin and gingiva of the left mandible. The lesions were macroscopically seen as grayish white papular granulomas, and microscopically consisted to numerous swollen macrophages and a few neutrophils without fibrocaseous necrosis. Macrophages contained many small oval or round-shaped yeast-like cells and a few rod-shaped organisms indicating a narrow based budding in their cytoplasm. The yeast-like cells were 2-5 microns (average 3.5 microns) in diameter, and appeared as a central, spherical, lightly basophilic body surrounded by a clear zone or "halo". The cell wall and central body were stained by the periodic acid-Shiff, Grocott's methenamine silver impregnation, or Gridley fungus method. Immunohistochemically, yeast-like cells were positive to anti-histoplasma yeast antibody, and rod-shaped organisms were positive to anti-histoplasma mycelial antibody. The present paper describes the first case of canine histoplasmosis in Japan.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9713818/