Peer-reviewed veterinary case report
High blood ferritin linked to shorter survival in dogs with lymphoma
By Chikazawa, Seishiro et al.·Published in The Journal of veterinary medical science·2015·Department of Small Animal Internal Medicine, Japan·View original on PubMed →
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Original publication title: Hyperferritinemia is associated with short survival time in dogs with multicentric lymphoma.
- Species:
- dog
Plain-English summary
A group of 18 dogs with multicentric lymphoma (a type of cancer affecting multiple lymph nodes) was studied to see how serum ferritin levels (a protein that can indicate inflammation or disease) affected their survival time. The dogs were divided into two groups based on their ferritin levels: those with high levels (3,000 ng/ml or more) had a median survival time of just 40 days, while those with low levels survived much longer, averaging 360 days. This suggests that high ferritin levels may indicate a shorter survival time in dogs with this type of cancer. More research is needed to confirm these findings.
People also search for: dog lymphoma survival time · high ferritin levels in dogs · multicentric lymphoma treatment options
Abstract
In the present study, we examined the relationship between serum ferritin concentration before treatment and survival time in dogs with multicentric lymphoma. Eighteen dogs with multicentric lymphoma were enrolled in the study. When the dogs were classified into high and low ferritin groups on the basis of their serum ferritin concentration (3,000 ng/ml cut-off value), the median survival time of dogs with high concentrations (≥3,000 ng/ml, n=7) was 40 days, whereas it was 360 days among dogs with low concentrations (<3,000 ng/ml, n=11). This difference was statistically significant (P=0.001). This finding suggests that the initial high level of serum ferritin indicates short survival time in dogs with multicentric lymphoma. Large-scale research is necessary to confirm this finding.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25715650/