Peer-reviewed veterinary case report
Hypergammaglobulinemia in an SIV-infected rhesus macaque with a B-cell neoplasm with plasma cell differentiation.
- Journal:
- Journal of medical primatology
- Year:
- 2011
- Authors:
- Kramer, Joshua A et al.
- Affiliation:
- Harvard Medical School · United States
Abstract
An SIV-infected rhesus macaque presented with anemia, hypercalcemia, and hyperglobulinemia. Neoplastic round cells with plasma cell morphology infiltrated multiple organs and stained immunohistochemically positive for CD45, MUM1/IRF4, CD138, VS38C, and Kappa light chain and variably positive for CD20 and CD79a, consistent with a B-cell neoplasm with plasma cell differentiation.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21401622/