Peer-reviewed veterinary case report
Hyperlocomotion Test for Assessing Behavioral Disorders.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2018
- Authors:
- Ma, Dan & Guest, Paul C
- Affiliation:
- Department of Neurosciences · United Kingdom
- Species:
- rodent
Abstract
Under- or overfeeding during pregnancy can lead to behavioral deficits in the offspring in later life. Here, we present a protocol for setting up and carrying out the hyperlocomotion test for assessing behavioral symptoms such as psychosis or mania. As an example, we use the acute rat phencyclidine-injection model which exhibits hyperlocomotion and stereotypic behaviors, resembling the positive symptoms of schizophrenia.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/29380332/