Peer-reviewed veterinary case report
Low cortisol from lymphoma caused Addison's disease in two cats
By Parnell, N K et al.·Published in Journal of the American Veterinary Medical Association·1999·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Hypoadrenocorticism as the primary manifestation of lymphoma in two cats.
- Species:
- cat
Plain-English summary
Two adult male domestic shorthair cats were brought to the vet showing signs of severe weakness, lack of appetite, weight loss, and lethargy. Tests revealed they had hypoadrenocorticism (a condition where the adrenal glands don't produce enough hormones) caused by lymphoma invading their adrenal glands. Initially, both cats responded well to treatment, but sadly, their owners decided to euthanize them. A necropsy confirmed that both cats had multicentric lymphoma affecting their adrenal tissue.
People also search for: cat lethargy and weight loss · cat hypoadrenocorticism treatment · lymphoma in cats symptoms
Abstract
Hypoadrenocorticism secondary to bilateral lymphomatous invasion of adrenocortical tissue was diagnosed in 2 adult castrated domestic shorthair cats. In both cats, findings during initial physical examination (ie, lethargy, anorexia, weight loss, and severe weakness) were consistent with severe hypoadrenocorticism. Hyperkalemia, hyponatremia, and azotemia were also detected, which were consistent with hypoadrenocorticism. Hypoadrenocorticism was documented on the basis of finding low baseline and ACTH-stimulated serum cortisol concentrations. The cats initially responded well to treatment, but both owners chose to have the cat euthanatized. Multicentric lymphoma with infiltration and destruction of the adrenal glands was confirmed during necropsy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10212685/