Peer-reviewed veterinary case report
Radiation therapy for microscopic soft tissue sarcoma in dogs
By Kung, M B J et al.·Published in Veterinary and comparative oncology·2016·Australian Animal Cancer Foundation, Australia·View original on PubMed →
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Original publication title: Hypofractionated radiation therapy for the treatment of microscopic canine soft tissue sarcoma.
- Species:
- dog
Plain-English summary
A group of dogs with soft tissue sarcomas (a type of cancer) that had not been completely removed by surgery received a special type of radiation therapy called hypofractionated radiation. This treatment involved fewer, larger doses of radiation over a shorter period, and it was found to be effective for many dogs. While some dogs did experience local recurrence or metastasis (spread of cancer), most had good long-term control of their tumors, with many living over a year after treatment. This approach can be a good option for older dogs or those with budget constraints.
People also search for: dog soft tissue sarcoma treatment · hypofractionated radiation for dogs · dog cancer survival rates
Abstract
Soft tissue sarcomas (STSs) are locally invasive and surgery with or without radiation therapy is the current standard of care in dogs. Typical protocols for treating incompletely excised STSs involve curative intent radiation with total dose in excess of 50 Gy. Forty-eight dogs with histologically confirmed incomplete or closely excised STSs were treated with a hypofractionated protocol that is typically reserved for palliative radiation therapy (RT) (6-8 Gy/weekly fractions to a total dose of 24-32 Gy). Ten dogs (21%) developed local recurrence, 11 dogs (23%) developed metastasis, and 3 dogs developed both (included in each group). The median progression free survival was 698 days. The local failure-free probability at 1 and 3 years was 81 and 73%. The 1 and 3 years tumour-specific overall survival was 81 and 61%. Long-term local tumour control was achieved in the majority of dogs. This protocol is reasonable to prescribe in older patients or when financial limitations exist.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25393921/