Peer-reviewed veterinary case report
Low blood sugar and muscle damage in cats after lisdexamfetamine
By Crecraft, Catherine et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2022·Department of Emergency and Critical Care, United States·View original on PubMed →
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Original publication title: Hypoglycemia and presumptive rhabdomyolysis secondary to lisdexamfetamine toxicosis in 3 cats.
- Species:
- cat
Plain-English summary
Three cats were brought to the vet after being exposed to a medication called lisdexamfetamine, which caused symptoms typical of amphetamine poisoning. During their hospital stay, the cats developed low blood sugar (hypoglycemia) and high levels of a muscle enzyme, indicating muscle damage (rhabdomyolysis). The veterinarians treated them with sedatives to help manage their symptoms. After a few days in the hospital, all three cats recovered and went home.
People also search for: cat low blood sugar treatment · cat muscle damage from medication · amphetamine poisoning in cats
Abstract
OBJECTIVE: To describe the clinical course and novel biochemical changes in 3 cats with lisdexamfetamine (LDX) toxicosis. SERIES SUMMARY: Three cats presented with LDX exposure and initially displayed typical clinical signs of amphetamine toxicosis. However, over the course of hospitalization, hypoglycemia and markedly elevated creatine kinase levels consistent with rhabdomyolysis ensued. All cats were treated with sedatives including phenothiazines and dexmedetomidine. Two cats were hospitalized for 4 days and 1 for 5 days. All cats survived. NEW OR UNIQUE INFORMATION PROVIDED: This is the first case series in cats that reports the novel biochemical changes of delayed hypoglycemia and elevated creatine kinase several days into hospitalization for the treatment of LDX toxicity. The development of delayed clinical signs suggests reconsideration of established hospitalization guidelines for amphetamine ingestion in cats.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34766711/