Peer-reviewed veterinary case report
Cat agitated and restless after lisdexamfetamine overdose helped
By Norkus, Christopher L et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2017·Allegheny Veterinary Emergency Trauma & Specialty, United States·View original on PubMed →
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Original publication title: Dexmedetomidine to control signs associated with lisdexamfetamine dimesylate toxidrome in a cat.
- Species:
- cat
Plain-English summary
A 5-month-old female domestic shorthaired cat showed signs of distress, including dilated pupils, agitation, and excessive movement after accidentally ingesting a medication called lisdexamfetamine. Despite receiving several treatments, including fluids and other medications, her condition worsened. However, when she was given dexmedetomidine, her symptoms quickly improved. After experiencing some vomiting and blood in her urine, she recovered well and was back to normal five days after leaving the vet.
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Abstract
A 5-month-old intact female domestic shorthaired cat had mydriasis, agitation, and increased locomotion after ingestion of lisdexamfetamine, 10.3 mg/kg body weight (BW). Despite treatment with IV fluids, IV acepromazine, oral cyproheptadine and intravenous lipid emulsion the patient's clinical signs worsened. Dexmedetomidine administered at 2 μg/kg BW and continued at 0.5 μg/kg BW per hour rapidly controlled the patient's signs. An episode of vomiting and hematuria developed. Follow-up 5 days after discharge revealed that the cat appeared normal.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28246413/