Peer-reviewed veterinary case report
Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China.
- Journal:
- Journal of veterinary science
- Year:
- 2018
- Authors:
- Shen, Hanqin et al.
- Affiliation:
- College of Animal Science & National Engineering Center for Swine Breeding Industry · China
Abstract
Recently, a novel atypical porcine pestivirus (APPV) in pig was reported. In this study, two APPV strains, APPV-China/GZ01/2016 (GZ01) and APPV-China/GD-SD/2016 (GD-SD), were identified in two newborn piglet herds with congenital tremor from China. The open reading frame of the two strains shared an 83.5% nucleotide identity. Phylogenetically, the APPV strains were placed into two groups: GZ01 belonged to group I and GD-SD belonged to group II. A high viral load was detected in the cerebellum (quantification cycles ＜ 26). Further studies should be carried out to thoroughly elucidate the development of congenital tremors caused by APPV.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/29284212/