Peer-reviewed veterinary case report
Phylogenetic and genomic characterization of a novel atypical porcine pestivirus in China.
- Journal:
- Transboundary and emerging diseases
- Year:
- 2018
- Authors:
- Zhang, H et al.
- Affiliation:
- Huazhong Agricultural University · China
Abstract
Atypical porcine pestivirus (APPV) has been considered a novel pestivirus and causative agent of congenital tremor type A-II. An APPV CH-GX2016 strain was characterized from newly born piglets with clinical symptoms of congenital tremor in Guangxi, China. The genome of APPV CH-GX 2016 strain was 11,475 bp in length and encoded a polyprotein composed of the 3,635 amino acids. This genome sequence exhibited 88.0% to 90.8% nucleotide sequence homology with other APPV reference sequences in GenBank. Phylogenetic analysis further showed that APPV CH-GX is a novel pestivirus compared with previously described classical pestivirus strains. Therefore, APPV is present in pigs in China.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28710801/