Peer-reviewed veterinary case report
Bacteria linked to chronic mouth inflammation in cats identified
By Dolieslager, Sanne M J et al.·Published in Veterinary microbiology·2011·University of Glasgow Dental School, United Kingdom·View original on PubMed →
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Original publication title: Identification of bacteria associated with feline chronic gingivostomatitis using culture-dependent and culture-independent methods.
- Species:
- cat
Plain-English summary
A 5-year-old cat with chronic gingivostomatitis (FCGS) was suffering from severe oral pain and inflammation. Researchers took oral swabs from both healthy cats and those with FCGS to identify the bacteria present. They found that a specific type of bacteria, Pasteurella multocida, was much more common in the cats with FCGS compared to healthy ones, suggesting it may play a significant role in this painful condition. Unfortunately, there are currently no specific treatments available for FCGS, but understanding the bacteria involved could help in future treatment options.
People also search for: cat gingivostomatitis treatment · cat oral pain bacteria · why does my cat have bad breath
Abstract
Feline chronic gingivostomatitis (FCGS) is a chronic inflammatory disease of the oral cavity that causes severe pain and distress. There are currently no specific treatment methods available and little is known regarding its aetiology, although bacteria are thought to play a major role. The purpose of this study was to identify the oral bacterial flora in normal and diseased cats. Oral swabs were obtained from the palatoglossal folds of eight cats (three normal and five FCGS) and were subjected to microbiological culture. Pasteurella pneumotropica and Pasteurella multocida subsp. multocida were the most prevalent species identified by culture methods in the normal and FCGS samples, respectively. Bacteria were also identified using culture-independent methods (bacterial 16S rRNA gene sequencing). For the normal samples, 158 clones were analysed and 85 clones were sequenced. Capnocytophaga canimorsus (10.8% of clones analysed) was the predominant species. Uncultured species accounted for 8.2% of clones analysed, and 43.7% of clones analysed represented potentially novel species. For the FCGS samples, 253 clones were analysed and 91 clones were sequenced. The predominant species was P. multocida subsp. multocida (51.8% of clones analysed). Uncultured species accounted for 8.7% of clones analysed, and 4.7% of clones analysed represented potentially novel species. It is concluded that the oral flora in cats with FCGS appears to be less diverse than that found in normal cats. However, P. multocida subsp. multocida is found to be significantly more prevalent in FCGS than in normal cats and consequently may be of aetiological significance in this disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20828946/