Peer-reviewed veterinary case report
Abyssinian cat with muscle weakness from polysaccharide storage
By Langohr, I M & Tanabe, M·Published in Veterinary pathology·2005·School of Veterinary Medicine, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Idiopathic complex polysaccharide storage disease in an abyssinian cat.
- Species:
- cat
Plain-English summary
A 10-year-old neutered Abyssinian cat was brought in after experiencing a gradual loss of movement that progressed to sudden paralysis over four years. The vet diagnosed the cat with a rare glycogen storage disease, which affects muscle function due to abnormal deposits of glycogen in the tissues. Unfortunately, the exact cause of this condition is still unknown, and while the cat's symptoms were identified, there is no specific treatment available to reverse the disease. The focus would be on managing the cat's symptoms and providing supportive care.
People also search for: Abyssinian cat paralysis treatment · cat muscle disease symptoms · glycogen storage disease in cats
Abstract
A glycogen storage disease affecting primarily the skeletal muscle and, to a lesser degree, the cardiac muscle, spinal cord, and brain was diagnosed in a 10-year-old neutered Abyssinian cat with a 4-year history of paresis progressing to acute paralysis. Microscopically, these tissues contained inclusions that were pale basophilic in hematoxylin and eosin-stained slides, diastase resistant, periodic acid-Schiff positive, and blue-to-almost black with iodine stain. By transmission electron microscopy, the inclusions consisted of cytosolic, usually sharply demarcated, nonmembrane-bound deposits of finely granular and filamentous material. On the basis of the structural and histochemical staining characteristics, the inclusions were believed to be aggregates of abnormally stored, unbranched glycogen. A defect in glucose metabolism is suspected to be the underlying pathologic process, but an exact cause remains elusive.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16006612/