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Peer-reviewed veterinary case report

Malignant nerve sheath tumor causing brain mass in young dog

By Shihab, Nadia et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2013·Department of Veterinary Clinical Sciences, United Kingdom·View original on PubMed

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Original publication title: Imaging diagnosis-malignant peripheral nerve sheath tumor presenting as an intra-axial brain mass in a young dog.

Species:
dog

Plain-English summary

A 3-year-old Labrador retriever started having seizures suddenly and was taken to the vet. An MRI showed a mass in the right side of the brain, which was later identified as a malignant peripheral nerve sheath tumor, a type of cancer. The dog had surgery to remove the tumor and initially seemed to recover, but unfortunately, three months later, the dog’s condition worsened, leading to euthanasia. A post-mortem confirmed the tumor's aggressive nature and its impact on the brain.

People also search for: dog seizures · Labrador brain tumor · malignant peripheral nerve sheath tumor in dogs · dog surgery recovery · dog euthanasia after surgery

Abstract

A 3-year-old Labrador retriever was presented with acute onset seizures. Magnetic resonance imaging demonstrated an intra-axial mass affecting the right temporal lobe of the brain. Surgical resection and histopathological findings were most consistent with a malignant peripheral nerve sheath tumor. After initial recovery, deterioration 3 months post surgery prompted euthanasia. Post-mortem revealed a mass protruding from the ventral surface of the temporal lobe, encroaching upon the optic chiasm and invading the brain. Histopathology findings were again consistent with malignant peripheral nerve sheath tumor. Although rare, this tumor should be included as a possible differential diagnosis for intra-axial brain masses in dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23363000/