Peer-reviewed veterinary case report
Survival and treatment outcomes in dogs with immune-mediated anemia
By Reimer, M E et al.·Published in Journal of the American Animal Hospital Association·1999·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Immune-mediated hemolytic anemia: 70 cases (1988-1996).
- Species:
- dog
Plain-English summary
A group of dogs diagnosed with immune-mediated hemolytic anemia (IMHA), a condition where the immune system attacks red blood cells, were treated with various medications to see how long they could survive. The results showed that dogs treated with prednisone and azathioprine had the best survival rates, living a median of 974 days, while those receiving no treatment only survived about one day. Unfortunately, the overall mortality rate was high, with 70% of the dogs either dying or needing to be euthanized during the study. Many of the dogs that were discharged from the hospital still faced serious health issues afterward.
People also search for: dog immune-mediated hemolytic anemia treatment · IMHA in dogs survival rate · prednisone for dog anemia
Abstract
Survival times and mortality rates in dogs with idiopathic immune-mediated hemolytic anemia (IMHA) have been infrequently reported in the literature. This study evaluates survival and mortality in a large group of dogs with IMHA. The association of age, sex, and breed with IMHA was evaluated by comparing affected dogs to control dogs admitted to the hospital during the same time period. Treatment regimens were reviewed to determine the effects of different agents upon survival of dogs with IMHA during hospitalization and after discharge. Median survival times for each treatment group were 57 days (prednisone), 28 days (prednisone, cyclophosphamide), 974 days (prednisone, azathioprine), 15 days (prednisone, cyclophosphamide, azathioprine), and one day (no treatment). Overall mortality rate in the population of dogs studied was 70%. Twenty-nine (41.4%) dogs either died or were euthanized while hospitalized. Forty-one (59%) dogs were discharged from the hospital. Of the dogs discharged, 10 died within the first month, another five died within three months, and another five died within a year of discharge due to assumed complications of therapy or relapses of IMHA.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10493413/