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Peer-reviewed veterinary case report

Immune low white cells and platelets in 3 giant schnauzers

By Vargo, Cheryl L et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2007·Department of Small Animal Clinical Sciences, Canada·View original on PubMed

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Original publication title: Immune mediated neutropenia and thrombocytopenia in 3 giant schnauzers.

Species:
dog

Plain-English summary

Three adult female giant schnauzers were brought to the vet with low white blood cell and platelet counts, along with an enlarged spleen. Two of the dogs tested positive for antibodies that attack their own white blood cells. After having their spleens removed, the dogs were treated with prednisone and azathioprine, which helped restore their blood cell levels to normal. All three dogs showed improvement and recovered well after treatment.

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Abstract

Neutropenia, thrombocytopenia, and splenomegaly were recognized in 3 adult female giant schnauzers. Antineutrophil antibodies were demonstrated in 2 dogs. Following splenectomy, administration of prednisone and azathioprine resulted in normalization of neutrophil and platelet numbers in all dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18050797/