Peer-reviewed veterinary case report
Immunohistochemical features of two feline odontogenic tumors
By Sakai, Hiroki et al.·Published in Journal of feline medicine and surgery·2008·Department of Veterinary Medicine, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Immunohistochemical features of proliferative marker and basement membrane components of two feline inductive odontogenic tumours.
- Species:
- cat
Plain-English summary
Two young male cats, aged 11 and 10 months, were brought to the vet with nasal swelling and a mass in the upper jaw. Upon examination, the vet found that both cats had a rare type of tumor called feline inductive odontogenic tumor (FIOT), which is usually benign. The tumors were invasive but showed low levels of cell proliferation, suggesting they were not aggressive. The cats were likely monitored for their condition, as these tumors can be managed without immediate aggressive treatment.
People also search for: cat nasal swelling · feline inductive odontogenic tumor treatment · cat mouth mass · benign tumors in cats
Abstract
Feline inductive odontogenic tumour (FIOT) is a rare and interesting odontogenic neoplasm in which the odontogenic epithelium has inductive potential to form aggregated foci of dental pulp-like mesenchymal cells. Two male cats aged 11 and 10 months presented with nasal swelling and a left maxillary mass. Histopathologically, the masses consisted of non-encapsulated invasive neoplasms exhibiting proliferation of epithelial and mesenchymal components with local infiltration into the maxillary bone in both cases. The epithelial component formed islands, anastomosing strands, and solid sheets of polygonal epithelial cells. Occasionally, these cells formed circular aggregates, resembling the cap stage of odontogenesis. Type IV collagen and laminin were constantly positive around the foci of epithelial cells, and Ki-67 positive indices were extremely low; therefore, these findings consistent with the benign clinical presentation of FIOT.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17766158/