Peer-reviewed veterinary case report
Dog with nerve tumor in left jaw diagnosed by special staining
By Fattahian, Hamidreza et al.·Published in Journal of the South African Veterinary Association·2012·Department of Surgery·View original on PubMed →
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Original publication title: Immunohistochemical study of a canine neurofibroma.
- Species:
- dog
Plain-English summary
A dog with a tumor in its jaw was diagnosed with a neurofibroma, a type of tumor that affects nerve tissue. The diagnosis was made using imaging tests and a detailed examination of the tumor after it was surgically removed. The tumor showed specific cell characteristics and tested positive for certain markers that helped confirm the diagnosis. After surgery, the dog was treated based on the findings, which can help in recognizing similar tumors in the future.
People also search for: dog jaw tumor diagnosis · neurofibroma in dogs · dog tumor surgery recovery
Abstract
Accurate diagnostic approaches to differentiate peripheral nerve sheet tumours from others have not been firmly established. The aim of this case report was to diagnose neurofibroma using a combination of diagnostic imaging, histopathology and immunohistochemistry, which were applied to a canine neurofibroma arising in the left mandible. The tumour was surgically excised and examined histologically. Round or spindle cells, with elongated, dense and homogenous chromatin and pale cytoplasm typical of Schwann cells in an abundant fibromyxomatous stroma, with ruby collagen fibres were seen. Immunohistochemistry demonstrated that S-100 and vimentin were more than 70% positive. Neurofibroma may therefore be recognisable using markers such as S-100 and vimentin.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23327147/