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Peer-reviewed veterinary case report

Pigmented skin tumor in 2-year-old German Shepherd dog

By Espinosa de los Monteros, A et al.·Published in Veterinary pathology·2000·View original on PubMed

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Original publication title: Immunohistopathologic characterization of a dermal melanocytoma-acanthoma in a German Shepherd Dog.

Species:
dog

Plain-English summary

A 2-year-old female German Shepherd was found to have a rare skin growth called a melanocytoma-acanthoma, which is a type of tumor made up of both skin and pigment cells. The tumor was examined and showed that it had two types of abnormal cells, but it appeared to be benign, meaning it was not cancerous and unlikely to spread. This type of skin issue is uncommon in dogs, but it can be managed effectively. The dog is expected to do well following treatment.

People also search for: German Shepherd skin tumor · dog melanocytoma treatment · benign skin growth in dogs

Abstract

A cutaneous melanocytoma-acanthoma in a 2-year-old female German Shepherd Dog was characterized by the presence of two populations of neoplastic cells: epithelial and melanocytic. The epithelial component consisted of nests of well-differentiated stratified squamous epithelium closely associated with neoplastic melanocytes. The epithelial cells immunoreacted with both monoclonal and polyclonal anti-cytokeratin antibodies, and immunoreaction to S-100 protein and vimentin was observed in the melanocytic cells. This rare pigmented skin neoplasm of the dog apparently has a benign behavior.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10810992/