Peer-reviewed veterinary case report
Glucan boosts puppy immunity after parvovirus and rabies vaccines
By Haladová, Eva et al.·Published in Acta veterinaria Hungarica·2011·Department of Epizootiology and Preventive Veterinary Medicine·View original on PubMed →
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Original publication title: Immunomodulatory effect of glucan on specific and nonspecific immunity after vaccination in puppies.
- Species:
- dog
Plain-English summary
A group of puppies received a vaccine for canine parvovirus and rabies, along with a syrup containing a substance called glucan, to see if it would boost their immune response. The puppies that got the glucan showed significantly higher levels of antibodies against these viruses compared to those that only received the vaccine. This suggests that glucan can help improve immunity in puppies, especially those with weakened immune systems. The study indicates that glucan could be a beneficial addition to vaccinations in young dogs.
People also search for: puppy vaccination immune support · glucan for dogs · canine parvovirus vaccine effectiveness · rabies vaccine for puppies
Abstract
The objective of the study was to determine the immunostimulatory effect of β-(1,3/1,6)-D-glucan in puppies. The effect exerted on the efficacy of vaccination, especially against canine parvovirus and rabies infection, was studied. The application of vaccine and glucan leads to significant increases in the nonspecific immunological parameters (phagocytic ability of leukocytes, blastogenic response of lymphocytes, metabolic and chemotactic activity of polymorphonuclear cells). The level of antibodies against canine parvovirus (Ab CPV) and rabies infection reached the most statistically significant values on the 28th day after the application of vaccine and a syrup containing β-(1,3/1,6)-D-glucan (Group GV) as compared to the control group (Group V, puppies receiving only vaccine). Dogs without glucan supplementation did not produce such significant levels of antibodies. We can conclude that glucan has relevant immunostimulatory effects in dogs with altered immunity. The glucan product tested in this study (PleraSAN V, PLEURAN, Bratislava, Slovakia) could be used in the small animal clinical practice.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21354943/