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Peer-reviewed veterinary case report

Immunoreactivity of bovine schwannomas.

Journal:
Journal of comparative pathology
Year:
2007
Authors:
Nielsen, A B et al.
Affiliation:
Department of Veterinary Pathobiology

Abstract

Thirty schwannomas from 22 cows were examined immunohistochemically. All were positive for vimentin and Ki-67 but negative for pancytokeratin, neurofilament, and desmin. S-100 immunolabelling varied between and within lesions. The numbers of tumours giving positive results for S-100, neuron-specific enolase (NSE) and glial fibrillary acidic protein (GFAP) were 16, 30 and 25, respectively. It was concluded that vimentin-positive tumours suspected to be schwannomas should also be immunolabelled for NSE and GFAP to confirm the diagnosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17888938/