Peer-reviewed veterinary case report
Higher CCR4+ immune cells and allergy antibodies in dogs
By Yamaya, Yoshiki & Watari, Toshihiro·Published in The Journal of veterinary medical science·2015·Department of Veterinary Medicine, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Increased proportions of CCR4(+) cells among peripheral blood CD4(+) cells and serum levels of allergen-specific IgE antibody in canine chronic rhinitis and bronchitis.
- Species:
- dog
Plain-English summary
A group of dogs with chronic rhinitis (nasal inflammation) and bronchitis (lung inflammation) showed signs that they might have allergies. Tests revealed that these dogs had higher levels of certain immune cells and allergen-specific antibodies in their blood, suggesting an allergic response. To help manage their symptoms, a treatment with macrolide antibiotics was found to be a good alternative to traditional corticosteroids. Many of these dogs experienced relief from their symptoms with this new approach.
People also search for: dog chronic rhinitis treatment · dog bronchitis symptoms · allergy treatment for dogs
Abstract
Canine chronic rhinitis (CR) and bronchitis (CB) are suspected to be allergic diseases. The present study tested whether dogs diagnosed with CR or CB present an atopic predisposition based on the ratio of CC chemokine receptor 4 (CCR4)-positive cells among peripheral blood CD4-positive cells (CCR4/CD4) and the serum levels of allergen-specific IgE antibodies. We found that most dogs with CR and CB have a possibility of atopic predisposition, and macrolide therapy constitutes an alternative to corticosteroid therapy in controlling the clinical signs.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25650058/