Peer-reviewed veterinary case report
Signs and outcomes of infiltrative laryngeal disease in dogs
By Dixon, A et al.·Published in The Journal of small animal practice·2020·Small Animal Referral Hospital, United Kingdom·View original on PubMed →
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Original publication title: Infiltrative laryngeal disease in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with breathing problems due to infiltrative laryngeal disease was studied, which included both inflammatory conditions and tumors. Most of the dogs had inflammatory issues, while two had tumors (one with lymphoma and one with a mast cell tumor). Out of the 15 dogs, 12 were able to go home after treatment, and some showed improvement over several months, although relapses were common. Unfortunately, the dogs with tumors had poor outcomes, with one being euthanized after eight months. Overall, while many dogs improved, ongoing monitoring is important due to the risk of recurrence.
People also search for: dog breathing problems · laryngeal disease in dogs · dog lymphoma treatment · mast cell tumor in dogs · dog throat inflammation symptoms
Abstract
OBJECTIVES: To describe the clinical features and outcome of neoplastic and inflammatory infiltrative laryngeal disease in dogs. MATERIALS AND METHODS: Medical records at a single referral centre were retrospectively reviewed for dogs diagnosed with infiltrative laryngeal disease by CT or laryngoscopy. RESULTS: Fifteen dogs were included, with a median age of 6 years (range 1-14 years). Thirteen dogs were diagnosed with inflammatory disease including granulation tissue (n = 4) and neutrophilic (n = 2), septic neutrophilic (n = 2), eosinophilic (n = 1) lymphocytic/plasmacytic (n = 1) and mixed/unclassified (n = 3) inflammation. One dog was diagnosed with large cell lymphoma and one dog was diagnosed with mast cell tumour. Twelve dogs survived to discharge. Follow-up was available for 10 dogs diagnosed with inflammatory disease. Four had fully recovered (7, 10, 23 and 32 months) and one dog developed acute leukaemia and was euthanased at 2 months. Five dogs had recurrence of clinical signs at 1, 1, 5, 17 and 26 months. The dog with lymphoma was euthanased at 8 months and the dog with mast cell tumour died at 5 months. CLINICAL SIGNIFICANCE: In this cohort, infiltrative inflammatory lesions of the larynx were more common than neoplastic infiltration. For dogs that survived to discharge, outcome was fair although relapse was common.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32715485/