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Peer-reviewed veterinary case report

Interdigital involvement in a case of primary cutaneous canine histoplasmosis in Japan.

Journal:
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine
Year:
2005
Authors:
Nishifuji, K et al.
Affiliation:
Department of Dermatology
Species:
dog

Abstract

A 5-year-old male Siberian husky bred outdoor in Tokyo had a swollen paw with interdigital granulomatous lesions in the left hindlimb. The dog had no apparent pulmonary or gastrointestinal involvement. Histopathological analysis of the skin lesions demonstrated yeast-like organisms predominantly within macrophages. Sequence analysis of fungal ribosome RNA gene isolated from a paraffin sample revealed a 100% homology with the teleomorph of Histoplasma capsulatum. The present case may support the concept of primary cutaneous canine histoplasmosis as an endemic phenotype recognized in Japan.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16268961/