Peer-reviewed veterinary case report
Dog with ivermectin poisoning treated with fat emulsion therapy
By E. Khaksar et al.·Published in Veterinary Medicine and Science·2025·View original on Semantic Scholar →
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Original publication title: Intralipid emulsion therapy for ivermectin toxicity in a dog
- Species:
- dog
Plain-English summary
A 3-year-old female Shih Tzu was brought to the vet after accidentally ingesting a 10 mg ivermectin tablet, showing symptoms like unsteady walking, tremors, and excessive drooling. The vet diagnosed her with ivermectin toxicity and started treatment with an intravenous lipid emulsion (ILE), which helped to counteract the effects of the poison. Remarkably, her neurological symptoms began to improve just 2.5 hours after starting the ILE therapy, and by the next day, she had fully recovered. This case highlights the effectiveness of ILE in treating certain types of drug toxicity in dogs.
People also search for: dog ivermectin toxicity treatment · Shih Tzu tremors after medication · how to treat dog poisoning
Abstract
ABSTRACT Objective Therapeutic management of ivermectin overdose in a Shih Tzu dog using intravenous administration of intravenous lipid emulsion (ILE). Case Summary A 3‐year‐old female Shih Tzu dog weighing 2.5 kg was presented to a veterinary clinic in Tehran with ataxia, tremors, incoordination, negative PLR and menace reflex, bradycardia and salivation. The patient was treated with a 10 mg ivermectin tablet with the brand name Medimect in the last 12 h. Following the diagnosis of ivermectin intoxication, treatment with ILE was initiated. ILE was administered as a bolus of 1.5 mL/kg in 1 min, followed by a dose of 0.25 mL/kg/min for 30 min as a CRI. The neurological symptoms of the patient began to decrease 2.5 h after the ILE therapy. Twenty‐four hours later, the patient was resuscitated, and all symptoms were resolved. Conclusion The current paper reports the successful treatment of ivermectin toxicity with ILE therapy in Iran. The education of veterinarians regarding the beneficial and varied roles of ILE therapy in different clinical settings is warranted, particularly in terms of the potential for ILE therapy to reverse the toxicities of various lipophilic drugs.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/40859605