Peer-reviewed veterinary case report
Dog with ivermectin poisoning treated with fat emulsion therapy
By Khaksar, Ehsan et al.·Published in Veterinary medicine and science·2025·Department of Veterinary Clinical Science·View original on PubMed →
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Original publication title: Intralipid emulsion therapy for ivermectin toxicity in a dog.
- Species:
- dog
Plain-English summary
A 3-year-old female Shih Tzu was brought to the vet after showing signs of ivermectin poisoning, including shaking, trouble walking, slow heart rate, and excessive drooling. The dog had recently ingested a 10 mg ivermectin tablet. To treat the toxicity, the vet administered an intravenous lipid emulsion (ILE) therapy, which started to improve the dog's symptoms within a few hours. After 24 hours of treatment, the Shih Tzu fully recovered and showed no remaining symptoms.
People also search for: Shih Tzu ivermectin poisoning treatment · dog shaking after ivermectin · dog drooling and incoordination treatment
Abstract
OBJECTIVE: Therapeutic management of ivermectin overdose in a Shih Tzu dog using intravenous administration of intravenous lipid emulsion (ILE). CASE SUMMARY: A 3-year-old female Shih Tzu dog weighing 2.5 kg was presented to a veterinary clinic in Tehran with ataxia, tremors, incoordination, negative PLR and menace reflex, bradycardia and salivation. The patient was treated with a 10 mg ivermectin tablet with the brand name Medimect in the last 12 h. Following the diagnosis of ivermectin intoxication, treatment with ILE was initiated. ILE was administered as a bolus of 1.5 mL/kg in 1 min, followed by a dose of 0.25 mL/kg/min for 30 min as a CRI. The neurological symptoms of the patient began to decrease 2.5 h after the ILE therapy. Twenty-four hours later, the patient was resuscitated, and all symptoms were resolved. CONCLUSION: The current paper reports the successful treatment of ivermectin toxicity with ILE therapy in Iran. The education of veterinarians regarding the beneficial and varied roles of ILE therapy in different clinical settings is warranted, particularly in terms of the potential for ILE therapy to reverse the toxicities of various lipophilic drugs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40859605/