Peer-reviewed veterinary case report
Intramedullary cisplatin chemo helped some dogs with bone cancer
By Hahn, K A et al.·Published in The Journal of small animal practice·1996·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Intramedullary cisplatin chemotherapy: experience in four dogs with osteosarcoma.
- Species:
- dog
Plain-English summary
A 7-year-old mixed-breed dog with advanced osteosarcoma (a type of bone cancer) was treated with intramedullary cisplatin chemotherapy because he couldn't have surgery. This treatment led to complete remission of the tumor in one dog and partial remission in another, while two dogs did not improve. The dog that achieved complete remission maintained good limb function for seven months and was found to be tumor-free when euthanized for unrelated reasons. These results suggest that intramedullary cisplatin could be a promising option for managing this type of cancer in dogs.
People also search for: dog osteosarcoma treatment · cisplatin for dogs cancer · dog bone cancer survival rates
Abstract
Single-agent intramedullary cisplatin chemotherapy provided effective localised control in two of four dogs with advanced stage osteosarcoma unable to withstand an amputation or limb-sparing surgery. Complete remission of the local neoplasm was observed in one of the four dogs, partial remission of the local neoplasm in one dog and progressive disease in the other two. Limb function was preserved in one dog for seven months and that dog was found to be tumour-free when euthanased due to unrelated causes. These preliminary results warrant further investigation into the use of intramedullary cisplatin chemotherapy in the localised management of canine appendicular osteosarcoma. It is possible that this mode of treatment may be combined with other treatments to maximise the survival (i.e., systemic control) in other dogs affected with appendicular osteosarcoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8731408/