Peer-reviewed veterinary case report
Intraocular sarcoma from ruptured lens in a rabbit eye
By Dickinson, Ryan et al.·Published in Veterinary ophthalmology·2013·University of Saskatchewan, Canada·View original on PubMed →
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Original publication title: Intraocular sarcoma associated with a rupture lens in a rabbit (Oryctolagus cuniculus).
- Species:
- rabbit
Plain-English summary
A 7-year-old spayed female rabbit was brought in with severe eye problems, including blindness in her right eye due to a ruptured lens. For six years, she showed signs of inflammation and debris in the eye, which was left untreated. After a thorough examination, the veterinarian performed surgery to remove the affected eye. The examination of the eye tissue revealed an intraocular sarcoma (a type of cancer) along with other serious eye issues. Unfortunately, the rabbit had significant damage, but the surgery was necessary to address the cancer and other complications.
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Abstract
This case report describes the clinical manifestations and ocular pathology of an intraocular sarcoma in a spayed female 7-year-old rabbit that developed clinical signs consistent with phacoclastic uveitis at 6 months of age, which was left untreated for most of the next 6 years. Ophthalmologic examination confirmed pupillary occlusion, aqueous flare, fibrin, and lens debris within the anterior chamber of the right eye. The right eye was blind and phthisical. The tentative clinical diagnosis was chronic phacoclastic uveitis, and a routine transconjunctival enucleation of the right eye was completed. The globe was formalin-fixed and submitted for histologic examination. Light microscopic examination revealed a ruptured cataractous lens, uveitis, retinal detachment, and an intraocular sarcoma centered around the lens. Immunohistochemical (IHC) staining was positive for smooth muscle actin and vimentin and negative for Desmin and cytokeratin intermediate filaments.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23734573/