Peer-reviewed veterinary case report
Dog with nerve lymphoma causing seizures and weakness
By Bush, William W et al.·Published in Journal of the American Animal Hospital Association·2003·Department of Clinical Studies, United States·View original on PubMed →
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Original publication title: Intravascular lymphoma involving the central and peripheral nervous systems in a dog.
- Species:
- dog
Plain-English summary
A 5-year-old mixed-breed dog was brought to the vet due to weakness in the back legs, coordination problems, increased sensitivity, and low platelet counts for the past five months, along with seizures that started two weeks prior. The vet found signs of serious issues in the dog's nervous system and other organs, leading to a diagnosis of intravascular lymphoma, a type of cancer affecting blood vessels. Despite treatment with chemotherapy drugs like prednisone, L-asparaginase, and vincristine, the dog's condition worsened, and he ultimately passed away. This case highlights the challenges of diagnosing and treating this aggressive cancer in dogs.
People also search for: dog seizures treatment · mixed-breed dog weakness · intravascular lymphoma in dogs · dog cancer symptoms · dog coordination problems
Abstract
A 5-year-old, castrated male mixed-breed dog was presented for paraparesis, ataxia, hyperesthesia, and thrombocytopenia of 5 months' duration and recurrent seizures during the preceding 2 weeks. Multifocal neurological, ophthalmological, pulmonary, and cardiac diseases were identified. Magnetic resonance imaging and cerebrospinal fluid analysis supported a tentative diagnosis of neoplastic or inflammatory disease. A computed tomography-guided biopsy provided both cytopathological and histopathological evidence of intravascular lymphoma. The disease progressed despite chemotherapy with prednisone, L-asparginase, and vincristine. Postmortem histopathological examinations suggested intravascular lymphoma in the central and peripheral nervous systems as well as in multiple other organ systems. This is the first description of an antemortem diagnosis and treatment of intravascular lymphoma involving the central nervous system of a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12549621/