Peer-reviewed veterinary case report
Dog with sudden blindness and red eyes caused by lymphoma in blood
By Cullen, C L et al.·Published in Journal of the American Animal Hospital Association·2000·Department of Veterinary Internal Medicine, Canada·View original on PubMed →
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Original publication title: Intravascular lymphoma presenting as bilateral panophthalmitis and retinal detachment in a dog.
- Species:
- dog
Plain-English summary
A 7-year-old spayed female boxer was brought in for sudden blindness and red, painful eyes that had developed over the past week. The vet found signs of severe eye inflammation and retinal detachment but couldn't initially identify any other health issues. The dog was treated with prednisone, a medication that suppresses the immune system, which helped her retinas reattach and restored her vision temporarily. Unfortunately, two months later, she became blind again and showed signs of serious illness. A postmortem exam revealed she had intravascular lymphoma, a type of cancer affecting multiple organs, including her eyes.
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Abstract
A seven-year-old, spayed female boxer was presented for sudden blindness and red eyes of one week's duration. Ophthalmic examination revealed bilateral uveitis with complete bullous retinal detachments. Initial diagnostic testing failed to reveal evidence of systemic disease. Cytopathology of subretinal aspirates confirmed the presence of macrophages with intracytoplasmic retinal pigment, epithelial and choroidal pigment, and monocytes. Tentative diagnoses were idiopathic uveitis and retinal detachment. The dog was treated with immunosuppressive doses of prednisone. The retinas reattached and vision returned. By two months, the dog became blind and systemically ill. Postmortem and histopathological examinations revealed intravascular lymphoma in multiple organs, including the eyes.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10914534/