Peer-reviewed veterinary case report
Cat with brain and kidney damage from malignant T-cell lymphoma
By Lapointe, J M et al.·Published in Veterinary pathology·1997·Veterinary Medical Teaching Hospital, United States·View original on PubMed →
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Original publication title: Intravascular malignant T-cell lymphoma (malignant angioendotheliomatosis) in a cat.
- Species:
- cat
Plain-English summary
A 7-year-old spayed female Siamese cat was brought in after showing signs of unsteady walking, circling to the right, and losing control of her bladder and bowels for a week. Tests revealed issues in her brain and kidneys, indicating a serious condition called malignant T-cell lymphoma, which is a type of cancer. Unfortunately, despite the findings, the cat did not survive, and the necropsy showed significant damage to her brain and kidneys due to the cancer.
People also search for: cat ataxia circling · Siamese cat kidney cancer · cat involuntary urination treatment
Abstract
A 7-year-old spayed female Siamese cat was presented with a 7-day history of ataxia, circling to the right, and involuntary micturition and defecation. Cerebrospinal fluid analysis showed increased protein content and relative eosinophilia. At necropsy, there was flattening of the cerebral cortical gyri of the right frontal and parietal lobes, and both kidneys had multiple wedge-shaped cortical indentations. Histologically, the cerebral cortex contained several extensive malacic foci, and the kidneys had multifocal parenchymal degeneration and atrophy. There was multifocal partial to complete thrombosis of renal interlobar arteries and of the right middle cerebral artery and meningeal branches; these thrombi contained large anaplastic round cells, which often invaded the arterial wall. Many smaller vessels within the kidneys and brain were occluded with clusters of similar cells, without thrombosis or vascular wall invasion. The neoplastic round cells had immunohistochemical staining properties of T lymphocytes.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9163885/