Peer-reviewed veterinary case report
Testing dog spinal fluid for astrovirus and bornavirus in unknown
By Collinet, Audrey et al.·Published in Journal of veterinary internal medicine·2020·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Investigation of astrovirus and bornavirus in the cerebrospinal fluid of dogs clinically diagnosed with meningoencephalitis of unknown etiology.
- Species:
- dog
Plain-English summary
A group of 25 dogs diagnosed with meningoencephalitis (inflammation of the brain and spinal cord) had their cerebrospinal fluid tested for two types of viruses, astrovirus and bornavirus. The tests showed that neither virus was present in the fluid of any of the dogs. This suggests that these viruses are not common causes of meningoencephalitis in dogs. If your dog is showing symptoms like seizures, confusion, or changes in behavior, it's important to consult your veterinarian for further evaluation and treatment options.
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Abstract
BACKGROUND: Non-suppurative encephalitides in a variety of species, including humans and dogs, have been linked to infection by astroviruses and bornaviruses. HYPOTHESIS/OBJECTIVES: To determine whether or not ribonucleic acid of astroviruses or bornaviruses was present in the cerebrospinal fluid (CSF) of dogs with clinically diagnosed meningoencephalomyelitis of unknown etiology (MUE). ANIMALS: Twenty-five client-owned dogs evaluated by CSF analysis at a single university referral hospital. METHODS: Prospective case-control study. Cerebrospinal fluid was collected from clinically diagnosed MUE and control cases and evaluated by reverse-transcriptase polymerase chain reaction for the presence of astrovirus and bornavirus. RESULTS: Neither astrovirus nor bornavirus nucleic acids were identified in CSF collected from 20 clinically diagnosed MUE and 5 control cases. CONCLUSIONS AND CLINICAL IMPORTANCE: The negative results of this investigation suggest that astrovirus and bornavirus are not commonly detectable in CSF of dogs with MUE.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31785029/