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Peer-reviewed veterinary case report

Dog had seizures and kidney failure after isoniazid poisoning

By Haburjak, J J & Spangler, W L·Published in The Journal of small animal practice·2002·Ocean Avenue Veterinary Hospital, United States·View original on PubMed

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Original publication title: Isoniazid-induced seizures with secondary rhabdomyolysis and associated acute renal failure in a dog.

Species:
dog

Plain-English summary

A dog experienced seizures after being exposed to isoniazid, a medication typically used for treating tuberculosis in humans. This led to muscle breakdown (rhabdomyolysis) and acute kidney failure. While these complications are rare in dogs, they can occur following seizures. The dog required veterinary care to manage the seizures and support kidney function.

People also search for: dog seizures treatment · isoniazid toxicity in dogs · dog kidney failure symptoms

Abstract

Isoniazid-induced seizures resulted in rhabdomyolysis and associated acute renal tubular necrosis in a dog. Rhabdomyolysis and myoglobinuric renal failure, although recognised in the dog, are reported infrequently as a consequence of seizures. The clinical presentation of isoniazid toxicity in a dog is described.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11996396/