Peer-reviewed veterinary case report
Cat with jaundice caused by bile duct lymphoma
By Namiki, Keita et al.·Published in The Journal of veterinary medical science·2024·North Lab, Japan·View original on PubMed →
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Original publication title: Jaundice caused by primary common bile duct lymphoma of a cat.
- Species:
- cat
Plain-English summary
A 10-year-old American Shorthair cat was brought in with a lack of appetite and yellowing of the skin and eyes (jaundice). An ultrasound showed that the wall of the common bile duct was thickened, indicating a serious issue. Unfortunately, during surgery, the growth was found to be difficult to remove, and the cat was euthanized for humane reasons. An autopsy revealed that the cat had a rare type of cancer called primary common bile duct lymphoma, which had spread to other organs. This case highlights the importance of considering bile duct lymphoma in cats showing signs of jaundice.
People also search for: cat jaundice causes · American Shorthair cancer symptoms · bile duct lymphoma in cats
Abstract
A 10-year-old American Shorthair cat presented with anorexia and jaundice, and echogenic evaluation revealed diffuse thickening of the common bile duct (CBD) wall. An exploratory laparotomy was conducted, the lesion was evaluated as difficult to remove, and the cat was euthanized and autopsied. Histologically, round neoplastic cells proliferated in the mucosa of the CBD and infiltrated the hepatic lobe, pancreas, and duodenum. Immunohistochemistry revealed that the neoplastic cells were positive for cytoplasmic-CD3 and granzyme B, and TCR-gamma clonal rearrangement was detected. Based on these findings, the neoplasia was diagnosed as a primary CBD lymphoma originating from cytotoxic T or natural killer cells. To the best of our knowledge, this is the first reported case of feline primary CBD lymphoma. Although rare, lymphoma of the CBD should be considered in cats with jaundice and thickening of the CBD.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38538328/