Peer-reviewed veterinary case report
Puppy with juvenile diabetes and pancreatic insufficiency causing
By Kang, Ji-Houn et al.·Published in The Journal of veterinary medical science·2008·College of Veterinary Medicine, South Korea·View original on PubMed →
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Original publication title: Juvenile diabetes mellitus accompanied by exocrine pancreatic insufficiency in a dog.
- Species:
- dog
Plain-English summary
A 6-month-old male crossbred dog was brought to the vet with symptoms including cloudy eyes from immature cataracts, diarrhea, and not growing as expected. Tests revealed he had juvenile diabetes mellitus (DM) and exocrine pancreatic insufficiency (EPI), which means his pancreas wasn't producing enough enzymes for digestion. The vet found that his insulin levels were low, and a closer look at his pancreas showed fewer cells than normal. Managing both conditions is important to help improve his health and prevent further complications.
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Abstract
A 6-month-old male crossbred dog weighing 0.78 kg was presented with acute bilateral immature cataracts, intermittent diarrhea and growth retardation. The clinical manifestations and laboratory findings were suggestive of concurrent juvenile diabetes mellitus (DM) and exocrine pancreatic insufficiency (EPI). Moreover, the DM was associated with a decreased level of serum insulin-like growth factor I. Histological examination revealed a markedly lower number of pancreatic islets and acinar cells. This case shows that juvenile-onset DM can occur simultaneously with EPI and result in growth retardation, acute cataract formation and a high cortisol concentration.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19122401/