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Peer-reviewed veterinary case report

Chronic kidney disease signs in young Boxer dogs under 5 years

By Chandler, M L et al.·Published in The Journal of small animal practice·2007·Hospital for Small Animals, United Kingdom·View original on PubMed

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Original publication title: Juvenile nephropathy in 37 boxer dogs.

Species:
dog

Plain-English summary

A group of 37 young Boxer dogs, all under five years old, were diagnosed with chronic kidney disease, showing symptoms like increased thirst, frequent urination, and poor appetite. Tests revealed issues such as high levels of waste in their blood, low urine concentration, and abnormal kidney structure. Unfortunately, the survival time for these dogs varied widely, with some living for only a short time after diagnosis while others managed to live for over five years. This study highlights the serious nature of kidney problems in young Boxers and the need for careful monitoring and management.

People also search for: Boxer dog kidney disease symptoms · young dog chronic kidney disease treatment · Boxer dog increased thirst and urination

Abstract

OBJECTIVES: The purpose of this study was to review and characterise the clinical presentation of young boxer dogs with chronic kidney disease referred to the authors' institutions. METHODS: Records were collected retrospectively from 37 boxer dogs, less than five years of age, which had presented with azotaemia, inappropriately low urine concentrating ability, and ultrasound or radiographic evidence of abnormal kidneys. RESULTS: Clinicopathological findings included azotaemia, hyperphosphataemia, anaemia, isosthenuria and proteinuria. Ultrasonographic findings included hyperechoic renal cortices, loss of corticomedullary junction definition, dilated pelves and irregularly shaped small kidneys. Renal histopathological findings included pericapsular and interstitial fibrosis, inflammatory cell infiltration, dilated tubules, sclerotic glomeruli and dystrophic calcification. Survival time of the dogs varied from zero to over five years after diagnosis. CLINICAL SIGNIFICANCE: This paper documents features of the presentation and progression of juvenile nephropathy in boxer dogs. While juvenile nephropathy has been reported in individual cases of boxer dogs previously, this is the first reported case series.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17727634/