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Peer-reviewed veterinary case report

Large granular lymphocyte tumor causing gut disease in Irish wolfhound

By Snead, Elisabeth C R·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2007·Department of Small Animal Clinical Sciences, Canada·View original on PubMed

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Original publication title: Large granular intestinal lymphosarcoma and leukemia in a dog.

Species:
dog
LymphomaStomach & digestionDogs

Plain-English summary

An Irish wolfhound was diagnosed with a rare type of cancer called large granular lymphocyte (LGL) tumor, which caused severe gastrointestinal issues and low platelet counts. The dog experienced a rapid decline in health, typical for this type of tumor. Unfortunately, due to the aggressive nature of the cancer, treatment options were limited, and the prognosis was poor.

People also search for: dog cancer symptoms · Irish wolfhound leukemia treatment · protein-losing enteropathy in dogs

Abstract

A rare, large granular lymphocyte (LGL) tumor causing a protein-losing enteropathy and thrombocytopenia was diagnosed in an Irish wolfhound. The case had an aggressive clinical course, like most LGL tumors in humans. Immunophenotyping suggested that the LGL tumor in this dog was derived from a natural-killer cell.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17824330/