Peer-reviewed veterinary case report
Dog with bladder and skin lymphoma treated with chemotherapy
By Adachi, Mami et al.·Published in The Journal of veterinary medical science·2022·Obihiro University of Agriculture and Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Large granular lymphocyte lymphoma in the skin and urinary bladder of a dog.
- Species:
- dog
Plain-English summary
A 10-year-old female Cavalier King Charles Spaniel was brought to the vet because she had blood in her urine, frequent urination, and a skin rash. After examining samples from her skin and bladder, the vet diagnosed her with large granular lymphocyte lymphoma, a type of cancer affecting both areas. She initially responded well to chemotherapy with nimustine for three months, but later developed more skin issues and bladder problems. Additional chemotherapy with various drugs helped her survive for 11 months before she passed away due to complications related to the cancer.
People also search for: dog blood in urine treatment · Cavalier King Charles Spaniel skin rash · lymphoma chemotherapy for dogs
Abstract
A 10-year-old female Cavalier King Charles Spaniel presented with hematuria, pollakiuria and skin rash. Based on the histopathological and cytological examination of the skin and bladder mucosa, the dog was diagnosed with large granular lymphocytic (LGL) lymphoma of the bladder and skin. The dog responded well to the initial chemotherapy with nimustine for 3 months. Since recurrence of skin erosion and bladder wall thickening were observed, the dog was subsequently administered chemotherapy with other anticancer drugs, including chlorambucil, vincristine, doxorubicin, L-asparaginase, cytosine arabinoside, and cyclophosphamide. The dog survived for 11 months and died due to tumor-related disseminated intravascular coagulation. This is the first report of a canine case of LGL lymphoma in the skin and bladder.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35082219/