Peer-reviewed veterinary case report
Laryngeal paralysis and megaesophagus in young Pyrenean mountain dogs
By Gabriel, A et al.·Published in The Journal of small animal practice·2006·Department of Small Animal Clinical Sciences·View original on PubMed →
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Original publication title: Laryngeal paralysis-polyneuropathy complex in young related Pyrenean mountain dogs.
- Species:
- dog
Plain-English summary
Six young Pyrenean mountain dogs were brought in with breathing difficulties due to laryngeal paralysis, along with issues like megaesophagus (enlarged esophagus). Tests showed nerve problems affecting their muscles, and samples indicated nerve degeneration. Unfortunately, all dogs faced a poor prognosis, with many not surviving past two years of age. This condition appears to be inherited, so owners of related dogs should be aware of these serious symptoms.
People also search for: Pyrenean mountain dog breathing problems · laryngeal paralysis in young dogs · megaesophagus treatment for dogs
Abstract
OBJECTIVES: To characterise clinical, electrophysiological and histopathological findings. To analyse pedigree information in six young related Pyrenean mountain dogs with laryngeal paralysis-polyneuropathy complex (LP-PNC). METHODS: A retrospective study of clinical records and pedigrees of six young related Pyrenean mountain dogs with LP-PNC was carried out. RESULTS: All dogs were presented with laryngeal paralysis and concurrent megaoesophagus. Electrodiagnostic testing was performed in three dogs and showed electrophysiological abnormalities in the distal appendicular muscles. Histopathological findings of peripheral nerve samples were dominated by distal axonal degeneration. Clinical, electrophysiological and histopathological findings were supportive of a diagnosis of degenerative, sensorimotor LP-PNC, similar to that reported in young dalmatians and rottweilers. All dogs died or were euthanased by two years of age. An autosomal recessive mode of inheritance was suspected based on pedigree analysis. CLINICAL SIGNIFICANCE: Congenital LP-PNC should be suspected in any young dog presenting with laryngeal dysfunction and other concurrent neurological abnormalities. The prognosis is usually poor.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16512846/