Peer-reviewed veterinary case report
Lipid-rich mammary gland tumor found in young female cat
By Kamstock, D A et al.·Published in Veterinary pathology·2005·Colorado State University, United States·View original on PubMed →
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Original publication title: Lipid-rich carcinoma of the mammary gland in a cat.
- Species:
- cat
Plain-English summary
A 1.5-year-old female cat was brought to the vet because of a noticeable lump on her belly. After surgery to remove the mass, tests showed it was a rare type of breast cancer called lipid-rich mammary carcinoma, which is characterized by abnormal cells with fatty contents. This type of cancer is unusual in cats, and the vet was able to confirm the diagnosis through various lab tests. The cat's overall health was good, but further treatment options would need to be discussed with the veterinarian.
People also search for: cat lump on belly · cat breast cancer symptoms · treatment for cat mammary carcinoma
Abstract
A 1.5-year-old female, intact, clinically healthy cat presented for a subcutaneous mass of the ventral abdomen. Surgical excision and microscopic examination of the mass were performed. Histologically, this was a discrete, unencapsulated, multilobular, expansile mass, which compressed the surrounding normal mammary tissue. Lobules were composed of tubuloacinar structures formed by atypical round to polygonal cells, which contained foamy to microvacuolated cytoplasm and variably sized, intracytoplasmic, distinct vacuoles causing nuclear peripheralization. Neoplastic cells demonstrated intense and diffuse immunoreactivity for cytokeratin and lacked immunoreactivity for vimentin. The vacuolar contents stained positively with Oil RedO and negatively with periodic acid-Schiff and Alcian blue stains. Histomorphologic, histochemical, and immunohistochemial analysis support a diagnosis of lipid-rich mammary carcinoma. This is the first report of a cat with a lipid-rich variant of mammary carcinoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15872384/